Evaluation of the efficacy of topical ethyl vanillate in treatment of vitiligo

Evaluation of the efficacy of topical ethyl vanillate in enhancing the effect of phothotherapy against vitilligo

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201107317160N1

Enrollment

Registered

2012-03-03

Start date

2012-02-29

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitiligo. Vitiligo

Interventions

Intervention 1: topical ethyl vanillate 20 percent on the lesion of one side twice daily for 3months. Intervention 2: topical eucerin (placebo) on the other side (same place) twice daily for 3 months.

Treatment - Drugs

Placebo

topical ethyl vanillate 20 percent on the lesion of one side twice daily for 3months

topical eucerin (placebo) on the other side (same place) twice daily for 3 months

Eligibility

Sex/Gender

All

Age

7 Years to 100 Years

Inclusion criteria

Inclusion criteria: Pateints with bilateral generalized depigmented lesions are selected among phototherapy patients. Pregnant women, children under 6 years of age, patients with past history of skin cancer, and patients taking immunosuppresive medications, are excluded from study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pigmentation of lesions. Timepoint: before intervention 1, 2, 3 months after intervention. Method of measurement: vitiligo area severity index scale.	—

Secondary

Measure	Time frame
Erythema of lesion. Timepoint: at the end of months 1, 2, 3 after intervention. Method of measurement: taking photo.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Kalafi Shotorbani

Shiraz university of medical sciences

kalafia@sums.ac.ir , amirkalafi@yahoo.com+98 71 1231 9049

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026