Recurrent aphthous stomatitis. Recurrent oral aphthae
Conditions
Interventions
Intervention 1: Intervention group: Turmeric Jel (topical) three time a day by a swap. Intervention 2: Control group: Placebo gel, three time a day (topical) by a swap.
Treatment - Drugs
Placebo
Intervention group: Turmeric Jel (topical) three time a day by a swap
Control group: Placebo gel, three time a day (topical) by a swap
Sponsors
Erphan Teb
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 50 Patients between 20 and 45 years old will be included if they present with 1–5 aphthous ulcers of less than 24 h duration. The ulcers diameter will not be greater than 6 mm and they do not suffer from acute or chronic diseases of the oral mucosa Patients will be excluded from the study if they have concurrent clinical conditions including serious liver, kidney, and heart dysfunctions or if they have ulcers as a manifestation of a systemic disease process such as ulcerative colitis, Crohn’s disease, Behcet’s syndrome, or serious anaemia. To minimize the effect of confounding variables in the psycho- physiological component of the study, the patients should not have a history of alcohol or drug abuse and should not take any narcotic analgesics. Patients will be excluded if they have a history of systemic immunosuppressive therapy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease of pain. Timepoint: Before treatment and days 2, 4, 6, 10 and 14 after treatment. Method of measurement: VAS rating scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Size of ulcers. Timepoint: Before drug application (day 0) and at days 2, 6, 10 and 14. Method of measurement: Diameters. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed