Infertility. Female infertility of other origin
Conditions
Interventions
Intervention 1: Intervention: Immediately after ovarian puncture, 300µ GCSF is injected into the uterine cavity. Intervention 2: Control group: no intervention.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: First time IVF due to infertility Moderate to severe endometriosis (according to laparoscopic criteria, moderate endometriosis was defined as Adhesion affecting Fallopian tubes or ovaries, and severe endometriosis was defined as the involvement of Fallopian tubes, ovaries, and cul-de-sac) Age 18-40 years Fertility due to endometriosis Moderate -to –severe endometriosis was characterized by endometrial glands and stroma at least 5 mm beneath the peritoneum or an ovarian endometriotic cyst (endometrioma)
Exclusion criteria
Exclusion criteria: Male factor infertility. Evidence of a significant decrease in the ovarian reserve (FSH>11, AMH<0.5, decreased AFC), Endocrine disorders (diabetes, thyroid diseases, hyperprolactinemia, hypothalamic amenorrhea, etc.) , confirmed medical and immunologic diseases (SLE, rheumatoid arthritis, antiphospholipid syndrome, cardiovascular, liver, and renal diseases), and congenital uterine anomalies and uterine cavity disorder (bicornuate uterus, unicornuate uterus, Asherman syndrome, myoma, polyps, etc.). Donation candidates (ovum donation and surrogate utrus) were also excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy. Timepoint: 3 weeks after embryo transfer. Method of measurement: Vaginal ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ladan Kashani
Tehran University of Medical Sciences
Outcome results
None listed