Female infertility. inability to achieve a pregnancy sterility, female NOS
Conditions
Interventions
Intervention 1: in group 1: Making endometrial injury by pipelle instrument in the follicular phase ( at days 4–6 and before FET).The LEI process will be performed with scratching endometrium by using
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
No minimum to 40 Years
Inclusion criteria
Inclusion criteria: Aged under 40 years old Hysterosalpingography (HSG) or hysteroscopy showed a normal uterine cavity Body Mass Index < 30 Have a history of one or more IVF failures Women who were not using Oral Contraceptives (OCP) or GnRH in previous ART cycle Have indication for LEI (Local Endometrial injury) Patients who had given their written, informed consent for participation
Exclusion criteria
Exclusion criteria: Intrauterine abnormalities shown in sonography or imaging such as myoma, Ascherman syndrome, etc ...), endometrial hyperplasia and cancer Active vaginal and cervical infections Systemic disease (systemic lupus eritematoso, Diabetes, Hypertension, etc ... )
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemical Pregnancy Rate. Timepoint: 2 weeks after FET. Method of measurement: Pregnancy test ( BHCG ).;Implantation Rate. Timepoint: 5 weeks after positive BHCG Test. Method of measurement: Trans Vaginal Sono. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ongoinig Pregnancy Rate. Timepoint: upto 12 weeks of gestation. Method of measurement: Diagnosis of gynecologist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Zahra Parsaeian
Arash Women 's Hospital
Outcome results
None listed