Depression. Other depressive episodes
Conditions
Interventions
Intervention 1: Intervention group: Inofolic Powder twice daily for 12 weeks. Intervention 2: Control group: Without intervention.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 18-40 years With mild to moderate depression BMI <= 30
Exclusion criteria
Exclusion criteria: Smoking Taking folate supplements in the last 3 months Metabolic and thyroid disorders Hyperprolactinemia Hypercortisolemia Severe depression Use of drugs affecting the nervous system (such as antidepressants and anti-anxiety drugs) Insulin use Lack of blood sugar control Intense physical activity Pregnancy Lactation History of mental health problems in first degree relatives, Other diseases in addition to depression
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the level of depression. Timepoint: Before and after intervention. Method of measurement: Hamilton Depression Rating Scale (HDRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| The blood tests for LDH,HDL,Total cholesterol ,TG, BMI, waist hip ratio , fasting glucose and insulin. Timepoint: Before and after the intervention. Method of measurement: The blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ladan Kashani
Tehran University of Medical Sciences
Outcome results
None listed