Infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: GnRH(0.1 mg/daily) will be injected from mid-luteal phase until mense then in the second day of menstrual cycle recombinant FSH with LH will be injected. When the s
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: The criteria for diagnosing poor ovarian response are two of the following:1- Age 40 or older 2 - History of poor ovarian response (POR) in the previous cycle (oocyte less than 3 in a conventional protocol), 3-Antral follicle count (AFC) less than 5-7 or Anti-Müllerian hormone (AMH) <0.5-1.1. Twice poor ovarian response after maximal ovarian stimulation is sufficient reason to introduce the individual as POR without the need for other criteria.
Exclusion criteria
Exclusion criteria: Polycystic ovarian syndrome Hypothalamic amenorrhea Uterine congenital anomalies and uterine cavity abnormalities (Bicorn uterus, Unicorn uterus, Asherman, Liomyuma, Polyp, etc.) Repeated IVF failure (more than three consecutive failures) Endocrine disorders (diabetes, thyroid disease, antipolipid syndrome, cardiovascular and liver disease),
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Embryo quality. Timepoint: Embryo formation. Method of measurement: By the embryologist.;Oocyte count. Timepoint: Puncture Day. Method of measurement: by embryologist. | — |
Primary
| Measure | Time frame |
|---|---|
| Number of mature oocytes. Timepoint: During IVF process. Method of measurement: Embryologist opinion.;Number of mature oocytes at retrieval. Timepoint: During IVF process. Method of measurement: Embryologist opinion. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLadan Kashani
Tehran University of Medical Sciences
Outcome results
None listed