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Effect of growth hormone in IVF protocol

Adjuvant growth hormone therapy in antagonist protocol in poor responders undergoing assisted reproductive technology

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201107296420N6
Enrollment
120
Registered
2011-08-21
Start date
2009-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Female infertility

Interventions

Intervention 1: In study group: Patients in group I (growth hormone group) receive daily injection of 4 mg growth hormone from day 21 of previous cycle until the day of hCG injection. Ovarian stimulat
Ovarian stimulation is started from second day of menstrual cycle with 300 IU of HMG monitoring by serial vaginal sonography and measurement of serum E2 levels is done. When dominant follicles reach t
Treatment - Drugs
In study group: Patients in group I (growth hormone group) receive daily injection of 4 mg growth hormone from day 21 of previous cycle until the day of hCG injection. Ovarian stimulation is started f
In control group: Patients in group II (control group)

Sponsors

Yazd research and clinical center for infertility
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: history of one or more failed in IVF cycles which three or fewer oocytes were been retrieved; serum steradiol’s level in day of HCG injection 10 and age>40 years. Exclusion criteria: Body mass index higher than 30; endocrine or metabolic disorder; endometriosis and severe male factor (azospermia ).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy. Timepoint: 2 weeks. Method of measurement: serum BHCG.

Secondary

MeasureTime frame
Number of oocyte. Timepoint: 15 days. Method of measurement: numberring.;Number of gonadotropin ampuls. Timepoint: 15 days. Method of measurement: numberring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Eftekhar

Yazd reaserch and clinical center for infertility

eftekhar@ssu.ac.ir+98 35 1824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026