Recurrent aphthous stomatitis. Aphthous stomatitis (minor)r
Conditions
Interventions
Intervention 1: Administration of Aloe-Vera oral gel (2%):
Using 50 ml pump-cap polystyrene containers the gel would be applied on the lesions 3 times a day for at least 10 days. Intervention 2: Admin
Treatment - Drugs
Placebo
Administration of Aloe-Vera oral gel (2%):
Using 50 ml pump-cap polystyrene containers the gel would be applied on the lesions 3 times a day for at least 10 days
Administration of Placebo (Lubricant oral gel containing 2% normal saline): Using 50 ml pump-cap polystyrene containers the placebo gel would applied on the lesions 3 times a day for at least 10 days
Sponsors
Deputy of Research; Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) Written consent 2) Age between 15-35 3) No systemic or oral cavity diseases except for RAS 4) Having singular minor recurrent aphtous on inner lips or cheeks since less than 48 h ago Exclusion Criteria: 1) Refusing to give written consent 2) Having any systemic or oral cavity diseases other than RAS minor 3) Aphthous stomatitis (major) 4) Having multiple RAS lesions in oral cavity 5) Pregnancy 6) Smoking
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stimulated pain score after. Timepoint: daily. Method of measurement: Visual Analogue Score.;Lesion and its surrounding inflammation diameters. Timepoint: Days: 0, 1, 3, 7 and 10. Method of measurement: Visual measurement using a metal caliper. | — |
Secondary
| Measure | Time frame |
|---|---|
| Healing period. Timepoint: end of treatment. Method of measurement: VAS <2 and lesions less than 1 mm diameter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Zabihi
Babol University of Medcial Sciences
Outcome results
None listed