Skip to content

Comparison of the effects of one-stage and quadrant-wise scaling and root planing on serum levels of serologic indices and clinical parameters in patients with periodontal disease

Comparison of the effects of one-stage full-mouth disinfection and quadrant-wise scaling and root planing on serum levels of IL-17 and IL-1ß and clinical parameters following treatment of moderate-to-severe chronic periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201107267128N1
Enrollment
40
Registered
2012-02-18
Start date
2010-04-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention:One-stage full-mouth disinfection. Intervention 2: Control:Quadrant-wise scaling and root planing.
Treatment - Other
Intervention:One-stage full-mouth disinfection
Control:Quadrant-wise scaling and root planing

Sponsors

Tabriz university of medical science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : A total of 20 patients, with an age range of 25-70 years, suffering from moderate-to-severe chronic periodontitis were randomly selected. The subjects had at least 12 teeth (irrespective of third molars and teeth with orthodontic appliances, bridgeworks, crowns and implants), with the 30% of the teeth with clinical attachment loss of =3 mm and radiographic evidence of bone loss in each group, as specified by the inclusion criteria. The exclusion criteria included systemic conditions, conditions which delay would healing, a history of radiotherapy or immune-suppressive treatment modalities, pregnancy or breast-feeling, use of systemic antibiotics during the two previous months, a history of continuous consumption of NSATDs and a history of scaling and root planing during the previous year

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum levels of IL-17 and IL-1ß. Timepoint: Base line,1month,4month. Method of measurement: ELIZA kit.

Secondary

MeasureTime frame
Clinical parameters of periodontium. Timepoint: Base line,1 month, 4 month. Method of measurement: Periodontal probing.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Reza Babaloo

Tabriz university of medical science

amirrezababaloo@yahoo.com+98 41 1335 5966

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026