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The Comparison of the Effect of Eccentric and Concentric Exercises to improve Function, Balance and Muscle Strength in Patients with Multiple Sclerosis

The Comparison of the Effect of Eccentric and Concentric Exercises to improve Function, Balance and Muscle Strength in Patients with Multiple Sclerosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201107261254N7
Enrollment
15
Registered
2011-11-05
Start date
2011-09-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Demyelinating diseases of the central nervous system

Interventions

Intervention 1: 30 minutes walking on treadmill with Positive slope (Concentric group), 3 times in a week, 4 weeks. Intervention 2: 30 minutes walking on treadmill with negative slope (Eccentric group
Rehabilitation
30 minutes walking on treadmill with Positive slope (Concentric group), 3 times in a week, 4 weeks
30 minutes walking on treadmill with negative slope (Eccentric group), 3 times a week, 4 weeks

Sponsors

Vice chancellor for research, Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Multiple Sclerosis patients with ability to walk 10 meter in a less than 1 minute (with or without aim) exclusion Criteria: Sever decrease of functional ability during last year; Pregnancy; Corticosteroid treatment during last month, Sever Psychological condition, Any conditions cause to prevent mild or moderate sport activities; regular sport activity twice a week for more than 10 minutes in each session; simultaneously present another medical condition such as diabetic; lower limb arthritis; unstable cardiovascular conditions that cause noncooperation of subject during intervention

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Two-Minute Walk. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: By meter.;Timed 25 Foot Walk. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: By chronometer.;Timed Get-up and Go. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: By Chronometer.;Static Balance Index. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: By Biodex Balance System.;Dynamic Balance Index. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: By Biodex Balance System.;Maximum isometric torque of quadriceps muscles. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: By Biodex Isokinetic Device 4Pro.;Maximum isometric torque of hamstring muscles. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: By Biodex Isokinetic Device 4Pro.

Secondary

MeasureTime frame
Disability Rate. Timepoint: Before and after intervention and also after 4 weeks follow-up. Method of measurement: Guy’s Neurological Disability Scale.;Ability rate. Timepoint: Before and after intervention and aslo after 4 weeks follow-up. Method of measurement: Rivermead Mobility Index (RMI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Hoshang Bakhtiary

Semnan University of Medical Sciences

amirbakhtiary@sem-ums.ac.ir; amir822@gmail.com; amir822@yahoo.com+98 23 1332 8502

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026