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The Effects of Barberry on Metabolic Syndrome Treatment

The Effects of Barberry Supplementation on Oxidative Indices in Patients with Metabolic Syndrome: A Randomized Double Blind Clinical Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110726007117N9
Enrollment
40
Registered
2020-03-25
Start date
2013-11-26
Completion date
Unknown
Last updated
2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome. Metabolic syndrome

Interventions

Intervention 1: Intervention group: Subjects in the intervention group receive Barberry capsules (daily intake of 600 mg) for 6 weeks (n=53). The participants take one capsule every day, which was con

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 18–65 years old Patients with Metabolic Syndrome according to the International Diabetic Federation criteria

Exclusion criteria

Exclusion criteria: Systemic diseases such as lupus, kidney disease, acquired immunodeficiency syndrome and rheumatoid arthritis Pregnant and lactating women Drug usage including consumption of the lipid-lowering, antihypertensive and antidiabetic drugs

Design outcomes

Primary

MeasureTime frame
Anti-Heat Shock Protein titre. Timepoint: Before the intervention and 6 weeks after taking drug or placebo. Method of measurement: Enzyme Linked Immunosorbent Assay.;Pro-Oxidant–Antioxidant Balance. Timepoint: Before the intervention and 6 weeks after taking drug or placebo. Method of measurement: Enzyme Linked Immunosorbent Assay.;Superoxide Dismutase. Timepoint: Before the intervention and 6 weeks after taking drug or placebo. Method of measurement: Spectrophotometry.

Secondary

MeasureTime frame
Serum Copper. Timepoint: Before the intervention and 6 weeks after taking drug or placebo. Method of measurement: Atomic Absorption.;Serum Zinc. Timepoint: Before the intervention and 6 weeks after taking drug or placebo. Method of measurement: Atomic Absorption.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Ghayour Mobarhan

Mashhad University of Medical Sciences

ghayourm@mums.ac.ir+98 51 3800 2288

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026