Covid-19 disease. Use this code when COVID-19 has been confirmed by laboratory testing irrespective of severity of clinical signs or symptoms. Use additional code, if desired, to identify pneumonia or other manifestations.
Conditions
Interventions
Intervention 1: Intervention group: 50000 International Unit (IU) pearl vitamin D as single dose, made in ZAHRAVI manufacture and then 10000 IU vitamin D syrup , 30 days, with lunch, Made in the depa
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Age 30- 60 years old Serum Vitamin D level lower than 30 nanograms per milliliter Cases who diagnosed as novel coronavirus 2019 infection by clinical features (sore throat, dry cough, dyspnea), laboratory findings (positive C- Reactive protein, lymphocyte<1100 per mililiter), or radiological findings (lung patchy infiltrations in chest X-ray or CT scan)
Exclusion criteria
Exclusion criteria: Serum Vitamin D level upper than 30 nanograms per milliliter Use of medications that interfere with vitamin D metabolism History of hypercalcemia, kidney disorders, cirrhosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C-Reactive Protein level. Timepoint: Measurement of C-Reactive Protein level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: enzyme-linked immunosorbent assay kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythrocyte Sedimentation Rate level. Timepoint: Measurement of Erythrocyte sedimentation level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: Westergren method.;Neutrophil to lymphocyte ratio level. Timepoint: Measurement of neutrophil to lymphocyte ratio level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: microscopic count.;Serum vitamin D level. Timepoint: Measurement of serum vitamin D level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: Enzyme-linked immunosorbent assay.;Low Density Lipoprotein Level. Timepoint: Measurement of Low Density Lipoprotein level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: Direct detergent method.;High Density Lipoprotein Level. Timepoint: Measurement of High Density Lipoprotein level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: Direct detergent method.;Total cholesterol level. Timepoint: Measurement of total cholesterol level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: Direct detergent method.;Triglyceride level. Timepoint: Measurement of tryglyserid level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: Direct detergent method.;Fasting Blood Glucose level. Timepoint: Measurement of Fasting Blood Glucose level before starting intervention and 30 days after starting the intake of vitamin D supplementation. Method of measurement: Enzymatic colorimetric method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDoctor Majid Ghayour Mobarhan
Mashhad University of Medical Sciences
Outcome results
None listed