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Effect of Saffron in Metabolic Syndrome

The Effects of Saffron Supplementation on Oxidative Indices in Patients with Metabolic Syndrome

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110726007117N10
Enrollment
30
Registered
2020-03-29
Start date
2010-08-23
Completion date
Unknown
Last updated
2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic Syndrome. Metabolic syndrome

Interventions

Intervention 1: Intervention group: Subjects in the intervention group receive Barberry capsules (daily intake of 100 mg) for 12 weeks (n=35). The participants take 2 capsule 50 mg every day, which wa

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 18–75 years old Patients with Metabolic Syndrome according to the International Diabetic Federation criteria

Exclusion criteria

Exclusion criteria: Systemic diseases such as lupus, kidney disease, acquired immunodeficiency syndrome and rheumatoid arthritis Pregnant and lactating women Drug usage including consumption of the lipid-lowering, antihypertensive and antidiabetic drugs

Design outcomes

Primary

MeasureTime frame
Anti-Heat Shock Protein titre. Timepoint: Before the intervention and 12 weeks after taking drug or placebo. Method of measurement: Enzyme Linked Immunosorbent Assay.;Pro-Oxidant–Antioxidant Balance. Timepoint: Before the intervention and 12 weeks after taking drug or placebo. Method of measurement: Enzyme Linked Immunosorbent Assay.;Superoxide Dismutase. Timepoint: Before the intervention and 12 weeks after taking drug or placebo. Method of measurement: Spectrophotometry.

Secondary

MeasureTime frame
Serum Copper. Timepoint: Before the intervention and 12 weeks after taking drug or placebo. Method of measurement: Atomic Absorption.;Serum Zinc. Timepoint: Before the intervention and 12 weeks after taking drug or placebo. Method of measurement: Atomic Absorption.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Ghayour-Mobarhan

Mashhad University of Medical Sciences

ghayourm@mums.ac.ir+98 51 3800 2288

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026