Comparison systemic blood pressure and heart rate change of two method spinal anesthesia in TURP surgery

A comparison hemodynamic change of minidose lidocaine-fentanil and conventional-dose lidocaine spinal anesthesia in patient with controlled systemic hypertension for TURP surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201107207064N1

Enrollment

148

Registered

2011-09-17

Start date

2011-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemodynamic change of spinal anesthesia in patient with controlled systemic hypertension and age>50 years.

Interventions

Spinal anesthesia with 1cc lidocaine 5% (50mg) + 1cc fentanyl 50 mcg (single dose). Lidocaine is a local anesthetic and fentanyl is a opium.

Spinal anesthesia with 2cc lidocaine 5% (100mg) single dose. Lidocaine is a local anesthetic.

Intervention 1: Spinal anesthesia with 1cc lidocaine 5% (50mg) + 1cc fentanyl 50 mcg (single dose). Lidocaine is a local anesthetic and fentanyl is a opium. Intervention 2: Spinal anesthesia with 2cc

Treatment - Drugs

Eligibility

Sex/Gender

Male

Age

50 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age>50 years; controlled systemic hypertension; TURP surgery; ASA class II Exclusion criteria: patient refusal; patient inability to maintain stillness during the needle puncture; raised intracranial pressure; coagulopathy; skin or soft tissue infection at the proposed site of needle insertion; severe hypovolemia; opium addiction; lumbar disc herniation or surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure. Timepoint: 5 Min. Method of measurement: Automatic cardioset monitoring.;Diastolic blood pressure. Timepoint: 5 Min. Method of measurement: Automatic cardioset monitoring.;Heart rate. Timepoint: 5 Min. Method of measurement: Automatic cardioset monitoring.	—

Secondary

Measure	Time frame
Ischemic heart disease and myocardial infarction. Timepoint: Every 8 Hr. Method of measurement: Serum CPK-MB and Troponin.;Acute tubular necrosis and acute renal failure. Timepoint: Daily. Method of measurement: Serum BUN and Creatinine.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahebanmaleki Mohsen

Gonabad University Of Medical Sciences

dr.saheban@gmu.ac.ir; dr.saheban@yahoo.com+98 53 3723 1112

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026