Electroconvulsive therapy plus olanzapine on patients with bipolar mood disorder

The efficacy of electroconvulsive therapy plus olanzapine on patients with bipolar mood disorder

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201107143930N8

Enrollment

Registered

2011-08-17

Start date

2011-07-07

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar Mood disorder. Bipolar affective disorder- Manic episode

Interventions

Intervention 1: ?ECT + olanzapine (5 to 10mg/day, PO, generally in 2 doses). Intervention 2: ECT + Placebo.

Treatment - Drugs

Placebo

?ECT + olanzapine (5 to 10mg/day, PO, generally in 2 doses)

ECT + Placebo

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusive criteria: age range of 17 to 60 years; None of them has contraindications for ECT taking and/or olanzapine under study. Exclusion criteria: pregnant and lactating women; clinically estimated mental retardation, and refusal of the patient or her or his legal representative for participation in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Young Mania Rating Scale. Timepoint: 4 weeks. Method of measurement: Interview.	—

Secondary

Measure	Time frame
Mini Mental Status Evaluation. Timepoint: before intervention, after every session of ECT. Method of measurement: Interview.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026