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Bupivacain and Fentanyl, before the start of surgery or before the end of surgery?

Comparison of efficacy of Bupivacain and Fentanyl in Pre-emptive and Pre-ventive Epidural Analgesia in the patients undergoing Major Gynecologic Surgeries.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201107127013N1
Enrollment
50
Registered
2011-12-31
Start date
2011-06-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

local analgesia in major gynecologic surgeries. Unspecified condition associated with female genital organs and menstrual cycle

Interventions

Intervention 1: 10 to 12 mls of Bupivacain 0.125 together with 25 micrograms of Fentanyl will be injected via epidural catheter as a bolus dose, 20 minutes before the end of the surgery for individual
Prevention
10 to 12 mls of Bupivacain 0.125 together with 25 micrograms of Fentanyl will be injected via epidural catheter as a bolus dose, 20 minutes before the end of the surgery for individuals in the group p
10 to 12 mls of bupivacain 0.125 and 25 micrograms of fentanyl as a bolus dose, 20 minutes before the initiation of the surgery and bupivacain 0.125 with a rate of 2 ml per minute as a continuous infu

Sponsors

Tabriz Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (being over 18 years; having indication for major gynecologic surgery) Exclution criteria: (to have a contraindication for epidural analgesia; to have allergy to local anesthetics; to have mental disorders; organic dysfunctions; previous chronic pain)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: 0, 3, 6, 12 and 24 hours after becoming conscious. Method of measurement: using visual pain scoring (VAS) from 0 (without pain) to 10 (severe intolerable pain).;Analgesics administered dose. Timepoint: 0-3-6-12-24 hours after becoming conscious. Method of measurement: Injection count and injection dose in milli or micro grams.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSimin Atashkhoyi

Tabriz Medical University

atashkhoii@tbzmed.ac.ir+98 41 1553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026