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The effect of dexmedetomidine and paracetamol on postoperative pain of cesarean section with spinal anesthesia

Comparing the effect of Dexmedetomidine-Paracetamol combination and placebo in prevention of postoperative pain in patients undergoing cesarean delivery with spinal anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110712007013N27
Enrollment
100
Registered
2020-04-08
Start date
2019-11-22
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute postoperative pain. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group: In this group 1 gr Paracetamol and 1 mg/kg Dexmedomidine in 100 ml normal saline is infused 15 minutes before the end of the surgery. Intervention 2: Control group:

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Pregnant women between the ages of 18 and 60 years old ASA class one and two Candidates for elective cesarean section or spinal anesthesia

Exclusion criteria

Exclusion criteria: Sensitivity to the compounds used for intervention group Mental illness Patients with cardiovascular, pulmonary, liver and kidney and ...disease Multiple pregnancy Urgent cesarean

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: At post-anesthesia care unit and at 1, 3, 6, 12 and 24 hours after surgery. Method of measurement: Visual analogue scale (VAS) (from 0= no pain to 10= severe pain).

Secondary

MeasureTime frame
Overall dose of postoperative analgesic. Timepoint: At post-anesthesia care unit and during 24 hours after surgery. Method of measurement: Number and amount of medication by mg, based on patient's record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Simin Atashkhoyi

Tabriz University of Medical Sciences

satashkhoyi@gmail.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026