Effect of administration of oxytocin and calcium chloride combination on blood loss

Effect of administration of oxytocin and calcium chloride combination on blood loss during abdominal myomectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110712007013N23

Enrollment

Registered

2019-07-06

Start date

2018-05-22

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood loss during Abdominal Myomectomy. N80-N98

Interventions

Intervention 1: Intervention group: Patients in the study group (25 cases), 30 units of oxytocin and 1 g of calcium chloride in 120 ml of normal saline serum in 120 minutes (at a rate of 1 ml / min) i

Eligibility

Sex/Gender

Female

Age

30 Years to No maximum

Inclusion criteria

Inclusion criteria: Healthy female abdominal myomectomy Age over 30 years Pre-operative ionized calcium values within normal range

Exclusion criteria

Exclusion criteria: Patients with a laparoscopic or hysteroscopic myomectomy candidate • Patients consuming GnRH agonist before surgery Patients with a history of heart, lung, kidney, liver, metabolic and ... History of oxytocin or calcium allergy Patients treated with digitalis drugs, ß-adrenergic blocker and calcium blocker Patients with coagulation disorders Thrombocytopenia (platelet 100000 / mm3>)

Design outcomes

Primary

Measure	Time frame
Low blood pressure. Timepoint: immediate after the intervention, after 5 minute, after 10 minute, after 20 minute, after 40 minute, after 60 minute, after 1.5 hour, after 2 hour, after 3 hour, . Method of measurement: Patient monitoring / Barometric device.;Tachycardia. Timepoint: immediate after the intervention, after 5 minute, after 10 minute, after 20 minute, after 40 minute, after 60 minute, after 1.5 hour, after 2 hour, after 3 hour, . Method of measurement: Patient monitoring.;Sweating. Timepoint: immediate after the intervention, after 5 minute, after 10 minute, after 20 minute, after 40 minute, after 60 minute, after 1.5 hour, after 2 hour, after 3 hour, . Method of measurement: Ask the patient.	—

Measure

Time frame

Low blood pressure. Timepoint: immediate after the intervention, after 5 minute, after 10 minute, after 20 minute, after 40 minute, after 60 minute, after 1.5 hour, after 2 hour, after 3 hour, . Method of measurement: Patient monitoring / Barometric device.;Tachycardia. Timepoint: immediate after the intervention, after 5 minute, after 10 minute, after 20 minute, after 40 minute, after 60 minute, after 1.5 hour, after 2 hour, after 3 hour, . Method of measurement: Patient monitoring.;Sweating. Timepoint: immediate after the intervention, after 5 minute, after 10 minute, after 20 minute, after 40 minute, after 60 minute, after 1.5 hour, after 2 hour, after 3 hour, . Method of measurement: Ask the patient.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSimin Atashkhoyi

Tabriz University of Medical Sciences

atashkhoii@tbzmed.ac.ir+98 41 1553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026