Comparison of the hemodynamic responses in tracheal intubation with glidescope or Macintosh in severe preeclampsy

Comparison the hemodynamic responses to laryngoscopy and tracheal intubation with glidescope or Macintosh laryngoscope in severe preeclamptic patients undergoing cesarean delivery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110712007013N20

Enrollment

Registered

2018-10-16

Start date

2018-04-21

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe preeclampsia. Severe pre-eclampsia

Interventions

Intervention 1: Intervention group: After 3 minutes preoxygenation with 100% O2 , general anesthesia is induced by Rapid sequence induction. After 60 seconds, the intubation is done by the Glidescope®

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Term pregnant women Age range 18-40 years old Candidates for elective or urgent cesarean section Severe preeclampsia Mallampati score I or II in preoperative visit informed consent

Exclusion criteria

Exclusion criteria: Mallampati score III or IV in preoperative visit Maternal co-existing disease History of cervical spine deformity or cervical motion limitation Eclampsia Coagulation disorder Body mass index (BMI) >30kg/m2 Recent use of vasoactive drugs

Design outcomes

Primary

Measure	Time frame
Hemodynamic responses to laryngoscopy with Glidescope(Non-invasive blood pressure (systolic, diastolic and mean arterial), heart rate and heart rhythm of the mother). Timepoint: Before induction of anesthesia (basic values), 30 seconds after administration of induction drugs, 15 seconds after the start of laryngoscopy, and then every 1 minute to 5 minutes after the tracheal intubation. Method of measurement: Non-invasive blood pressure (systolic, diastolic and mean arterial), heart rate, and heart rhythm are measured using the Datex Ohmeda S / 5 Anesthesia Machine and will be recorded in the checklist for this purpose.	—

Measure

Time frame

Hemodynamic responses to laryngoscopy with Glidescope(Non-invasive blood pressure (systolic, diastolic and mean arterial), heart rate and heart rhythm of the mother). Timepoint: Before induction of anesthesia (basic values), 30 seconds after administration of induction drugs, 15 seconds after the start of laryngoscopy, and then every 1 minute to 5 minutes after the tracheal intubation. Method of measurement: Non-invasive blood pressure (systolic, diastolic and mean arterial), heart rate, and heart rhythm are measured using the Datex Ohmeda S / 5 Anesthesia Machine and will be recorded in the checklist for this purpose.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSimin Atashkhoyi

Tabriz University of Medical Sciences

re.abri@tbzmed.ac.ir+98 41 3553 9163

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026