Effect of Berebris vulgaris on Metabolic Syndrome Components

Clinical Trial of the Effect of Processed Berberis vulgaris in Apple Vinegar and Apple Vinegar on Lipid Profile, Insulin Resistance, Weight, Hypertension and Inflammatory Indices in Type II Diabetic Patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201107096984N1

Enrollment

Registered

2011-07-16

Start date

2006-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabete. Diabetes Mellitus

Interventions

Intervention 1: Processed Berberis vulgaris in domestic apple vinegar- one table spoon with lunch for 8 weeks. Intervention 2: Domestic Apple Vinegar- 2 table spoon with lunch for 8 weeks.

Prevention

Processed Berberis vulgaris in domestic apple vinegar- one table spoon with lunch for 8 weeks

Domestic Apple Vinegar- 2 table spoon with lunch for 8 weeks

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: obesity (BMI>30kg/m2) or WHR>0.9(men) and 0.8(women); hypertriglyceridemia (TG>150 mg/dl); HDL90/140mmHg. Exclusion criteria: renal, hepatic, gastrointestinal and thyroid disease; diet therapy; insulin therapy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Glucose. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Blood pressure. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Manometer.;Malondialdehyde. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Inflammatoru indices. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Insulin. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Anthropometric Indices. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Bioelectric impedance.;Lipid profile. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.	—

Measure

Time frame

Glucose. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Blood pressure. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Manometer.;Malondialdehyde. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Inflammatoru indices. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Insulin. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.;Anthropometric Indices. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Bioelectric impedance.;Lipid profile. Timepoint: Baseline and 2, 4 and 8 weeka after intervention. Method of measurement: Biochemistery analysis.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdieh Golzarand

Obesity Research Center, Research Institue for Endocrine Science, Shaheed Beheshti University of Med

mahdieh_golzarand@yahoo.com+98 21 2243 2500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026