Skip to content

Efficacy of two drug regimens in the treatment of pneumonia

Comparison of efficacy in therapy with cefixime plus azithromycin versus high-dose amoxicillin plus azithromycin among patients with pneumonia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201107096922N2
Enrollment
82
Registered
2011-08-08
Start date
2008-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Efficacy of cefixime in pneumonia treatment. Bacterial pneumonia, not elsewhere classified & Bacterial pneumonia, unspecified

Interventions

Intervention 1: Cefixime 400mg / day orally for 10 days + Azithromycine 500 mg stat and 250mg daily orally. Intervention 2: Amoxicillin 1gr TDS for 10 days orally + Azithromycine 500 mg stat and 250mg
Treatment - Drugs
Cefixime 400mg / day orally for 10 days + Azithromycine 500 mg stat and 250mg daily orally
Amoxicillin 1gr TDS for 10 days orally + Azithromycine 500 mg stat and 250mg daily orally

Sponsors

Zanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 82 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: out-patients with pneumonia, age over 12 years Exclusion criteria: inpatients with pneumonia; Failure to refer the patient

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Patient's general appearance. Timepoint: after 1 week and after the treatment (10th day). Method of measurement: physical exam.;Fever. Timepoint: after 1 week and after the treatment (10th day). Method of measurement: termometer.;Cough. Timepoint: after 1 week and after the treatment (10th day). Method of measurement: patient's complaint and daily notes.;Lung auscultation to normal. Timepoint: after 1 week and after the treatment (10th day). Method of measurement: lung auscultation with stetoscope.

Secondary

MeasureTime frame
Shock. Timepoint: after 1 week and after the treatment (10th day). Method of measurement: measurement of BP.;Respiratory failure. Timepoint: after 1 week and after the treatment (10th day). Method of measurement: physical exam.;Level of consiousness. Timepoint: after 1 week and after the treatment (10th day). Method of measurement: physical exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfsaneh Karami

Zanjan University of Medical Sciences

Rastin@zums.ac.ir Dr.akarami@yahoo.com+98 24 1727 0801

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026