Skip to content

The comparison of different prophylactic techniques in hypotension due to spinal anesthesia on mother"s hemodynamic changes and neonatal outcome in cesarean section

The comparison of different prophylactic techniques in hypotension due to spinal anesthesia on blood pressure and heart rate of parturients undergoing cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201107062405N7
Enrollment
300
Registered
2011-07-13
Start date
2004-05-31
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of anaesthesia during pregnancy. Other complications of anaesthesia during pregnancy

Interventions

Intervention 1: Ringer's lactate (RL) solution (15 ml/kg) was infused. Duration of treatment: single dose in 30 minutes before spinal injection + mid thigh-high lower extremities bandage was performe
Prevention
Ringer's lactate (RL) solution (15 ml/kg) was infused. Duration of treatment: single dose in 30 minutes before spinal injection + mid thigh-high lower extremities bandage was performed immediately af
Colloid solution (Hemaxel) (7ml/kg) was infused. Duration of treatment: single dose in 30 minutes before spinal injection + mid thigh-high lower extremities bandage was performed immediately after spi
Ephedrine (15 mg, IV, bolus) was infused in 45 seconds. Duration of treatment: single dose Immediately after spinal injection+ mid thigh-high lower extremities bandage was performed immediately after
Ringer's lactate (RL) solution (15 ml/kg) was infused. Duration of treatment: single dose in 30 minutes before spinal injection + colloid solution (Hemaxel) (7ml/kg) was infused. Duration of treatment
Ringer's lactate (RL) solution (15 ml/kg) was infused. Duration of treatment: single dose in 30 minutes before spinal injection + Ephedrine (15 mg, IV, bolus) was infused in 45 seconds. Duration of tr
Colloid solution (Hemaxel) (7ml/kg) was infused. Duration of treatment: single dose in 30 minutes before spinal injection + Ephedrine (15 mg, IV, bolus) was infused in 45 seconds. Duration of treatmen

Sponsors

Vice chancellor for research- Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Parturients; ASA physical status I-II; scheduled for elective cesarean section; under spinal anesthesia; Exclusion Criteria: suspicious to bleeding disturbances; atopia; diabetes mellitus; presence of liver or kidney diseases; drugs abuse; hypertension of pregnancy; preeclampsia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: On arrival to operating room, immediately after anesthesia (time 0), and minutes 3, 5, 15, 20, 25, 30, 35, and 60 after spinal injection. Method of measurement: Using mercury manometer.;Heart rate. Timepoint: On arrival to operating room, immediately after anesthesia (time 0), and minutes 3, 5, 15, 20, 25, 30, 35, and 60 after spinal injection. Method of measurement: Using EKG Monitoring.

Secondary

MeasureTime frame
Apgar score. Timepoint: at min 1 and 5. Method of measurement: Apgar score mesurements by physical examination.;NACS. Timepoint: at 15 minutes, 2 hours, and 24 hours after delivery. Method of measurement: NACS mesurements by physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mitra Jabalameli

Isfahan University of Medical Sciences

jabalameli@med.mui.ac.ir+98 31162555551532

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026