agitation. agitation
Conditions
Interventions
Intervention 1: Patients were First group received intravenously midazolam. Midazolam dose was 0.3mg/kg in 30 minutes and then 0.1mg/kg per hour infusion until patient's agitation score become zero. I
Treatment - Drugs
Patients were First group received intravenously midazolam. Midazolam dose was 0.3mg/kg in 30 minutes and then 0.1mg/kg per hour infusion until patient's agitation score become zero.
The second group received intravenously midazolam plus vitamin C. dose was 0.3mg/kg in 30 minutes and then 0.1mg/kg per hour infusion. And vitamin C dose was 500mg in 30 minutes and then 250mg per hou
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients between ages 18-40; opioid abusers; coming to the hospital with withdrawal symptoms including agitation; caused by misusing of naltrexone. Exclusion criteria: Patients who had an underlying medical disorder (diabetic mellitus, renal failure, cardiovascular disease, renal stone and those undergo dialysis); pregnant women; those who were very agitated and need intubation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Agitation. Timepoint: every one hour. Method of measurement: RAAS score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rhabdomyolysis. Timepoint: after first 24 hours. Method of measurement: urine analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNastaran Eizadi-Mood
Isfahan University of Medical Sciences
Outcome results
None listed