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Efficacy of pretreatment by medicines on post endodontic pain

Efficacy of pretreatment by Celecoxib and Gelofen on post endodontic pain

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201106306926N1
Enrollment
90
Registered
2011-07-23
Start date
2009-07-27
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endodontic pain. Disorder of teeth and supporting structures, unspecified

Interventions

Intervention 1: Gelofena as capsule 400 mg, oral, one dose 2 houres before starting the treatment. Intervention 2: placebo as capsule, oral one dose 2 houres before starting the treatment. Interventio
Treatment - Drugs
Placebo
Gelofena as capsule 400 mg, oral, one dose 2 houres before starting the treatment
placebo as capsule, oral one dose 2 houres before starting the treatment
Celecoxib as capsule 200mg, per oral one dose 2 houres before starting the treatment

Sponsors

Vice chancellor for research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18 to 65; and having vital premolars of mandible or maxilla without any pre apical lesion Exclusion criteria: pregnancy; allergy to sulfonamide and NSAIDs; history of asthma related to nasal polyp; history of chronic using of analgesics; alcohol using; uncontrollable high blood pressure; diabetes mellitus; systemic disease and not using analgesic medicine 12 hours before study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 4, 8, 12, 24 and 48 hours after intervention. Method of measurement: VAS scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShaghayegh Nooribayat

Dental student of Research Committee, Dental Faculty, Babol University of Medical Sciences

dr.sh.noori@gmail.com; sh.nooribayat@mubabol.ac.ir+98 12 1225 1451

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026