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The impact of vitamins and antioxidants on the severity of endometriosis, pelvic pain in women

Effects of vitamin E and C supplements on serum levels of biomarkers of oxidative stress and pelvic pain in women with endometriosis symptoms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201106296917N1
Enrollment
Unknown
Registered
2015-10-12
Start date
2015-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometriosis. n80.9

Interventions

Intervention 1: Intervention group 1: In this study, the purpose of oral administration of vitamin E 800 units (two tablets of 400 IU) twice a day for 8 weeks and vitamin c tablets a day to 1000 mg (4
Placebo
Treatment - Drugs
Intervention group 1: In this study, the purpose of oral administration of vitamin E 800 units (two tablets of 400 IU) twice a day for 8 weeks and vitamin c tablets a day to 1000 mg (4 tablets of 250
Control group: Taking 2 pills placebo vitamin E (400 IU) and 800 units of 4 placebo vitamin C (250 mg), a total of 1000 mg daily for 8 weeks.

Sponsors

Iran University of Medical Sciences- Sarem Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: No current infection or a history of pelvic inflammatory disease during the study; Adenomyosis of disease, lack of supplementation in the last six months, not smoking, alcohol, lack of underlying chronic disease or mental illness known to his remarks patient, not a specific diet) such as a vegetarian diet); women with dysmenorrhea, irregular menstruation, lack of passing clots during menstruation. Exclusion criteria from the study: The patient's unwillingness to continue the research, side effects and drug allergy (such as fatigue, headache, blurred vision, nausea, diarrhea), the occurrence of pregnancy, diagnosed in the laparoscopy Adenomyosis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Bio-markers of oxidative stress. Timepoint: Two months before the intervention and after intervention. Method of measurement: Biomarker of oxidative stress in vitro assay kit.

Secondary

MeasureTime frame
Severe pelvic pain. Timepoint: bi-weekly. Method of measurement: Visual analogue instruments.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactchekini razieh

Iran University of Medical Sciences, School of Nursing and Midwifery

r.chekini@gmail .com+98 21 8888 2886

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026