Pregnancy, childbirth and the puerperium. Medical abortion
Conditions
Interventions
Intervention 1: Vaginal misoprostol + sublingual placebo tablet. Tablet misoprostol is prescribe in the form vaginal, is a prostaglandin group, 200 micrograms. Interval of prescription is every 3 hour
Treatment - Drugs
Vaginal misoprostol + sublingual placebo tablet. Tablet misoprostol is prescribe in the form vaginal, is a prostaglandin group, 200 micrograms. Interval of prescription is every 3 hours to 24 hours an
Sublingual misoprostol + vaginal placebo . Tablet misoprostol tablet is prescribe in the form sublingual , prostaglandin group, 200 microgram. Interval of prescription is every 3 hours to 24 hours and
Sponsors
Vice Chancellor for research, Guilan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : 12-24 weeks single pregnancy confirmed with certain LMP and > 20 weeks sonography Exclusion criteria : Known sensitivity to prostaglandins (questions such as skin rash, wheels, dyspnea, cough, chest pain, blurred vision); previous caesarian section; Vaginal bleeding; placenta previa; Parity > 3
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparing the effect of vaginal versus sublingual misoprostol in termination of pregnancy. Timepoint: Each 3 hours to 24 hours then if the pregnancy isn’t terminated misoprostol will be continued each 3 hours to 48 hours. Method of measurement: Observation of fetus expulsion. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determining the relative frequency of Abortion within 48 hours after using vaginal misoprostol. Timepoint: Each 3 hours to 48 hours after using sublingual misoprostol. Method of measurement: Measuring the time interval between using sublingual misoprostol to abortion.;Comparing the relative frequency of abortion within 24 hours in vaginal and sublingual misoprostol using. Timepoint: Each 3 hours to 24 hours. Method of measurement: Measuring the time interval between using vaginal misoprostol and sublingual misoprostol to abortion.;Determining the relative frequency of Abortion within 24 hours after using vaginal misoprostol. Timepoint: Each 3 hours to 24 hours. Method of measurement: Measuring the time interval between using vaginal misoprostol to abortion.;Determining the relative frequency of Abortion within 24 hours after using sublingual misoprostol. Timepoint: Each 3 hours to 24 hours. Method of measurement: Measuring the time interval between using sublingual misoprostol to abortion.;Determining the relative frequency of Abortion within 48 hours after using vaginal misoprostol. Timepoint: Each 3 hours to 48 hours after using sublingual misoprostol. Method of measurement: Measuring the time interval between using sublingual misoprostol to abortion.;Comparing the relative frequency of abortion within 48 hours after using vaginal and sublingual misoprostol. Timepoint: 3 hours to 48 hours after using vaginal and sublingual misoprostol. Method of measurement: Measuring the time interval between using vaginal and sublingual misoprostol to abortion.;Measuring the time interval after using vaginal misoprostol to pain onset. Timepoint: Each 3 hours. Method of measurement: Pain visual scale.;Measuring the time interval after using sublingual misoprostol to pain onset. Timepoint: Each 3 hours. Method of measurement: Pain visual scale.;Comparing the time interval between use vaginal and sublingual misoprostol and pain onset. Timepoint: Each 3 hours. Method of measureme | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Forozan Milani
Guilan University of Medical Sciences
Outcome results
None listed