Effects of Nigella Sativa in Obese Women

Effects of Nigella Sativa Oil Suplementation with Weight Loss Diet on Some Anthropometric Indices, Lipd Profile and Some Inflammatory Factors in Obese Women with Various Polymorphisms of Adiponectin gene and Type 2 Isoform Peroxisome proliferator-activated receptor gamma

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201106191197N10

Enrollment

Registered

2013-12-17

Start date

2013-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Obesity due to excess calories

Interventions

Intervention 1: Intervention group: Comsumption of 3 gr/day Nigella Sativa oil provided by Daana pharmaceutical company(1 gr soft gel capsule 3 times a day) with weight loss diet for 2 months. Interv

Placebo

Intervention group: Comsumption of 3 gr/day Nigella Sativa oil provided by Daana pharmaceutical company(1 gr soft gel capsule 3 times a day) with weight loss diet for 2 months

Control group: 3 gr/day sunflower oil provided by Daana pharmaceutical company(1 gr soft gel capsule 3 times a day) with weight loss diet

Eligibility

Sex/Gender

Female

Age

25 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: women with 25-50 years old; Body Mass Index between 30 to 34.9 kg/m2; following no weight loss diet or any special diet during 6 months ago. Exclusion criteria: taking vitamin-mineral supplement during 3 months ago;taking anti-inflammatory medications, losing weight drugs, asprin and other anticoagulant medications; cardiovascular diseases, liver, kidney and tyroid disorders,type 1 or 2 diabetes; pregnancy and lactation; smoking

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Anthropometric indices. Timepoint: Beginning and at the end of the intervention(after 2 months). Method of measurement: Height,weight,waist circumference,hip circumference mesearment.;Inflammatory factors. Timepoint: Beginning and at the end of the intervention( after 2 months). Method of measurement: Measurement of IL-6,TNF-a and hs-CRP with special kits.;Lipid profile. Timepoint: Begining and at the end of study(2 months). Method of measurement: Measurment of HDL-C,LDL-C,TG,TC with special kits.	—

Measure

Time frame

Anthropometric indices. Timepoint: Beginning and at the end of the intervention(after 2 months). Method of measurement: Height,weight,waist circumference,hip circumference mesearment.;Inflammatory factors. Timepoint: Beginning and at the end of the intervention( after 2 months). Method of measurement: Measurement of IL-6,TNF-a and hs-CRP with special kits.;Lipid profile. Timepoint: Begining and at the end of study(2 months). Method of measurement: Measurment of HDL-C,LDL-C,TG,TC with special kits.

—

Secondary

Measure	Time frame
Frequency of adiponectin and PPAR gamma-2 genotypes. Timepoint: Begining of intervention. Method of measurement: PCR-RFLP.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazli Namazi

Tabriz University of Medical Sciences, Health and nutrition faculty

nazli.namazi@yahoo.com+98 41 1334 1113

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026