Lowering ureter spasm to increase success rate in ureteroscopy and to remove stone

Investigating local effect of aminophylline on transureteral lithotripsy (TUL)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201106146803N1

Enrollment

120

Registered

2011-07-22

Start date

2011-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ureter stone. Calculus of ureter, Ureteric stone

Interventions

Intervention 1: After draining the bladder by catheter, 150 cc Study irrigation solutions was entered the bladder through ureteroscopy. Study irrigation solution in the intervention group was normal s

Treatment - Surgery

After draining the bladder by catheter, 150 cc Study irrigation solutions was entered the bladder through ureteroscopy. Study irrigation solution in the intervention group was normal saline+ 250 mg am

After draining the bladder by catheter, 150 cc Study irrigation solutions was entered the bladder through ureteroscopy. Study irrigation solution in the control group was normal saline. After five min

Eligibility

Sex/Gender

All

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: signing written Informed consent, ASA class ?-??, Age between 15 and 45 years, Elective surgery, Lower ureteral stones smaller than 20 mm Exclusion criteria: history of renal colic, history of TUL, renal anatomical abnormalities, renal malfunction, use of NSAIDs, steroids and opioids, Hypersensitivity to theophylline or any component of the formulation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Decreasing ureter espasm. Timepoint: once, during surgary. Method of measurement: increase succes rate in ureteroscopy and tul.	—

Secondary

Measure	Time frame
Time of TUL. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of need for ESWL. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of need for ureter stent. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of need for ureter catheter. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of the need for DJ. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of ureter evulsion. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of Acute pyelonephritis. Timepoint: after surgery. Method of measurement: Recorded in the questionnaire.;Success rate of stone removal. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.	—

Measure

Time frame

Time of TUL. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of need for ESWL. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of need for ureter stent. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of need for ureter catheter. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of the need for DJ. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of ureter evulsion. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.;Rate of Acute pyelonephritis. Timepoint: after surgery. Method of measurement: Recorded in the questionnaire.;Success rate of stone removal. Timepoint: once, during surgary. Method of measurement: Recorded in the questionnaire.

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Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026