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The comparison between effect of orally propranolol lorazpam and propranolol-lorazpam in reduction of preoperative anexiety

The comparison between effect of oral propranolol, lorazpam and propranolol-lorazpam in reduction of preoperative anexiety

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201106146256N2
Enrollment
75
Registered
2011-06-19
Start date
2009-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurotic, stress-related and somatoform disorders. Phobic anxiety disorder, unspecified

Interventions

Intervention 1: Intervention:inderal 20mg. Intervention 2: Intervention:lorazpam2mg. Intervention 3: Intervention:inderal20 mg+lorazpam2 mg.
Prevention
Intervention:inderal 20mg
Intervention:lorazpam2mg
Intervention:inderal20 mg+lorazpam2 mg

Sponsors

vice-chancellor for research of Qazvin universityof medical science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Grasp testimonial; elective minor to moderate surgery as: inguinal hernia, trans urethral lithothomy , colles fx, tibia fx; age 18-45 and ASA class Iand II Exclusion criteria: History of chronic consumption of bzd antipsychotics, opium and amphetamines; history of panic attack or any psychologic disorder; history of CHF, asthma COPD ,dm type Iand II; history of hypertension; history of any anti hypertension drug consumption and history of any food and drugs allergy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Preoprative stress score. Timepoint: 10 hours. Method of measurement: APIAS SCALE.

Secondary

MeasureTime frame
Blood pressure. Timepoint: 15 mint. Method of measurement: Non-Invasive Blood Pressure (NIBP).;Heart rate. Timepoint: 15min. Method of measurement: beat/min.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Behname Mahmoodieh

Qazvin, University of Medical Science

Bmahmoodieh@qums.ac.ir+98 28 1332 0107

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026