Comparing the efficacy of Ibuprofen and Celecoxib on the intensity of perineal pain following episiotomy

Comparing the efficacy of Ibuprofen and Celecoxib on the intensity of perineal pain following episiotomy: a single blind, randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201106136790N1

Enrollment

170

Registered

2012-08-14

Start date

2009-03-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post episiotomy pain. Other complications of obstetric surgery and procedures

Interventions

Intervention 1: Ibuprofen (400 mg), every 6 and 12 hours as necessary. Intervention 2: Celecoxib (100mg), orally, 6 and 12 hours as necessary.

Treatment - Drugs

Ibuprofen (400 mg), every 6 and 12 hours as necessary

Celecoxib (100mg), orally, 6 and 12 hours as necessary

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1-18-35 y/o; 2-mediolateral episiotomy; 3-singleton; 4- alive fetus. Exclusion criteria: 1-sensitivity to NSAIDs; 2-history of digestive system disorders; 3-presence of chronic illness; 4-rupture of cervix; 5-post partum hemorrhage; 6-pre eclampcia and eclampcia; 7-PROM.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain severity. Timepoint: pre intervention,1, 2, 4, 8 and 12 hours after intervention. Method of measurement: VAS.	—

Secondary

Measure	Time frame
Digestive system complications. Timepoint: Every 12 hours. Method of measurement: History and Physical exam.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZainab Suhrabi

Ilam University of Medical Sciences

suhrabi-z@medilam.ac.ir ; suhrabi2007@yahoo.com+98 84 1222 7123

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026