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Pain on Injection

Effect of ondansetron on injection pain caused by Etomidate

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201106125140N4
Enrollment
20
Registered
2012-09-25
Start date
2012-05-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain prevented in healthy subjects after injection. Unspecified complication following infusion, transfusion and therapeutic injection

Interventions

Intervention 1: Intervention:. 8mg (2 mL) of ondansetron was administered from one hand. Intervention 2: Control: 2ml of 0.9% saline from the other hand at the same time.
Prevention
Placebo
Intervention:. 8mg (2 mL) of ondansetron was administered from one hand.
Control: 2ml of 0.9% saline from the other hand at the same time.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Society of Anesthesiologists(ASA) physical status class I or II. Exclusion Criteria: patients with a history of thrombophebitis or vascular disease; chronic pain; diabetes mellitus; history of tumors or burns in either hands; history of addiction; any contraindications to injection of ondansetron or etomidate.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 2 minutes after injection. Method of measurement: visual analogue scale.

Secondary

MeasureTime frame
Urticaria. Timepoint: 30 minutes after ondansetron. Method of measurement: documenting any urticaria on thorax and around the neck.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Movafegh

Department of Anesthesiology, Dr. Shariati Hospital

movafegh@sina.tums.ac.ir+98 21 8490 2372

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026