Oral Mucositis. Other and unspecified lesions of oral mucosa
Conditions
Interventions
Intervention 1: A gel which was equalized in taste, odor, shape and color to 2% Calendula mouthwash was used as a placebo mouthwash. Patients were instructed to use the mouthwash 3 three times daily f
Placebo
Treatment - Drugs
A gel which was equalized in taste, odor, shape and color to 2% Calendula mouthwash was used as a placebo mouthwash. Patients were instructed to use the mouthwash 3 three times daily from onset of rad
Herbal extract of plant Calendula officinalis was added to a basic gel to make 2% calendula mouthwash. Patients were instructed to use the mouthwash 3 three times daily from onset of radio-therapy for
Sponsors
Vice chancellor for research, Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) Minimum accumulative dose of 40 Gy according to treatment protocol; 2) Complete exposure of oral field to x ray; 3) Minimum age of 45; Exclusion criteria were: 1) Pregnancy; 2) Allergy to the mouthwash; 3) Preexisting oral conditions; 4) Use of other medications related to oral mucositis during study period; 5) Any systemic diseases interfering with healing
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of oral mucositis. Timepoint: at the end of each week for total of 6 weeks for each patient. Method of measurement: Oral Mucositis Assessment Scale (OMAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNeda Babaee
Department of oral diseases, Dental School of Babol University of Medical Sciences
Outcome results
None listed