nephrotic syndrome.
Conditions
Interventions
In patients with relapse of NS,the relapse episode is controled with prednisolone 40 mg/m2/day for 7-10 days and then levamisole 2.5 mg/m2/every other day is administered while prednisolone is tapered
Treatment - Drugs
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 14 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: idiopathic nephrotic syndrome;frequent relapses or dependency to steroid;age 1-14 years old. Exclusion criteria: the patients who consume levamizole less than 6 months;need to start other immunosupressive drugs to control the relapses.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of relapses of nephrotic syndrom. Timepoint: during the whole period of study. Method of measurement: in relapses/year.;Cumulative dose of prednisolone. Timepoint: durig the whole period of the study. Method of measurement: in mg/kg body weight/year. | — |
Secondary
| Measure | Time frame |
|---|---|
| Neutropenia. Timepoint: every 4 months. Method of measurement: CBC.;Liver enzymes elevation. Timepoint: every 4 months. Method of measurement: AST,ALT.;Seizure. Timepoint: during the study period. Method of measurement: clinical. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Abolhassan Seyedzadeh
Kermanshah University of Medical Sciences
Outcome results
None listed