Endometriosis. Endometriosis
Conditions
Interventions
Intervention 1: Intervention group: A 250 mg capsule containing 200 µg of amino selenium enriched with Saccharomyces cerevisiae yeast was made at the Tabriz Nutrition Research Center and will be used
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 49 Years
Inclusion criteria
Inclusion criteria: Women of reproductive age (15-49 years) Being literate in reading and writing Women with primary endometriosis with endometrioma less than 5 cm Women with symptomatic endometriosis (dysmenorrhoea pain score of 16 or more in the Mous Menstrual Distress Questionnaire) Married women who are sexually active
Exclusion criteria
Exclusion criteria: Probability of malignancy based on vaginal ultrasound Definite need for surgery based on the opinion of obstetrician and gynecologist Suffering from diseases such as myoma or hyperplasia or polycystic ovary syndrome based on vaginal ultrasound Daily and regular consumption of supplements containing Amino Selenium during the last three months according to the patient's statement Suffering from liver and kidney diseases and the need for dialysis Pregnancy and breastfeeding Desire to get pregnant in the next trimester Allergy to Gelofen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average endometrioma cyst size. Timepoint: Before the intervention and 3 months after the start of intervention. Method of measurement: Vaginal ultrasound.;Average dysmenorrhea score. Timepoint: Monthly during 3 months (1, 2, 3 months) after the start of the intervention. Method of measurement: Mous Menstrual Distress Questionnaire (MMDQ). | — |
Secondary
| Measure | Time frame |
|---|---|
| Average dyspareunia score. Timepoint: Monthly during 3 months (1, 2, 3 months) after the start of the intervention. Method of measurement: Visual analog scale (VAS).;Average score of dysuria. Timepoint: Monthly during 3 months (1, 2, 3 months) after the start of the intervention. Method of measurement: Visual analog scale (VAS).;Average score of Dyschezia. Timepoint: Monthly during 3 months (1, 2, 3 months) after the start of the intervention. Method of measurement: Visual analog scale (VAS).;Average score of non cyclic pain. Timepoint: Monthly during 3 months (1, 2, 3 months) after the start of the intervention. Method of measurement: Visual analog scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Teihoomanesh fard
Tabriz University of Medical Sciences
Outcome results
None listed