Skip to content

The effect of probiotic supplementation on pregnancy outcomes in mothers with mild preeclampsia

Study of the effect of synbiotic supplementation on pregnancy outcomes in mothers with mild preeclampsia : A triple blind randomized controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110606006709N20
Enrollment
128
Registered
2019-09-25
Start date
2019-10-22
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild preeclampsia. Mild to moderate pre-eclampsia

Interventions

Intervention 1: Intervention group:The intervention group of the LactoCare synbiotic capsule made by the "Zist-takhmir" company, which contains the highest amounts of beneficial bacteria (lactobacilli

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women with mild preeclampsia singleton pregnancy with live fetus Gestational age more than 24 weeks Women with first pregnancy (Noliparus) Suitable maternal and fetal conditions for expectant management

Exclusion criteria

Exclusion criteria: Women with cardiovascular disease Women with renal and hepatic dysfunction Extreme and chronic hypertension Gestational diabetes mellitus and chronic History of probiotic susceptibility Use of antibiotics over the past two weeks

Design outcomes

Primary

MeasureTime frame
Mean systolic and diastolic blood pressure. Timepoint: Blood pressure will be measured before, during and after the study. Method of measurement: Measurement of blood pressure by ISOMED mercuric barometric device.;Mean duration of pregnancy from diagnosis to delivery. Timepoint: A the time of delivery. Method of measurement: Duration of pregnancy by calculating LMP or first trimester ultrasound.;Mean of newborn weight at birth. Timepoint: A the time of delivery. Method of measurement: Measurement of birth weight by SECA scales.

Secondary

MeasureTime frame
Detection of severe preeclampsia. Timepoint: During the study. Method of measurement: Criteria for the diagnosis of severe preeclampsia in the questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRouhina Movaghar

Tabriz University of Medical Sciences

Rouhin66@gmail.com+98 41 3476 9372

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026