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The effect of lactulose on administration on nitrogen waste products

The effect of lactulose on administration on nitrogen waste products in patients with chronic renal failure

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201105316666N1
Enrollment
40
Registered
2012-01-07
Start date
2011-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Chrontic Renal Failure stages 3. Condition 2: Chronic Renal Failure (stage 4). Moderate Chronic Renal Failure (stage 3) Severe Chronic Renal Failure (stage 4)

Interventions

Lactolose suspension 30 ml/min three times a day for two months.
Treatment - Drugs
Lactolose suspension 30 ml/min three times a day for two months

Sponsors

Tabriz University Of Medical Sciences and Health Services
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria :1)The patients with stages 3 and 4 of CRF 2The patients who are older than 18 years of age3) The patients who have consent to continue the study. Exclusion criteria:1) History of any probiotic, sinbiotic and antibiotic use during one month prior to the study2) patients with intolerance to lactolose or patients how create complications.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
P-cresyl sulfate. Timepoint: at the end of the study and 1 month after the study. Method of measurement: at the end of the study and 1 month after the study.;Indoxyl sulfate. Timepoint: at the end of the study and 1 month after the study. Method of measurement: High Performance Liquid Chromatography = HPLC.;Advanaced Glycation End (AGE) Products. Timepoint: at the end of the study and 1 month after the study. Method of measurement: High Performance Liquid Chromatography = HPLC.

Secondary

MeasureTime frame
C-Reactive Protein = CRP. Timepoint: at the end of the study and after 1 month. Method of measurement: Standard lab test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Bita Rahbari

Tabriz University Of Medical Sciences and Health Services

Rahbarib@tbzmed.ac.ir+98 41 1335 5921

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026