children urinary tract infection. Acute nephritic syndrome with unspecified morphologic changes
Conditions
Interventions
Intervention 1: Dexamethasone o.15 mg/kg q6h and Ceftriaxone 80 mg/kg/day in intervention group for 4 days. Intervention 2: Control group: 80 mg/kg/day ceftriaxone and placebo ( normal saline) i
Treatment - Drugs
Placebo
Dexamethasone o.15 mg/kg q6h and Ceftriaxone 80 mg/kg/day in intervention group for 4 days
Control group: 80 mg/kg/day ceftriaxone and placebo ( normal saline) in control group fot 4 days
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Months to 12 Years
Inclusion criteria
Inclusion criteria: All of children with acute Pyelonephritis 3months to 12 years old
Exclusion criteria
Exclusion criteria: Previous urinary tract infection Urinary tract anomalies renal failure renal scar Consumed antibiotic
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary IL6 and IL8 evaluate by ELISA. Timepoint: before and after treatment. Method of measurement: laboratory.;Renal scaring. Timepoint: befor and 4 month after treatment. Method of measurement: isotop scan. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects. Timepoint: during treatment. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactJavad Ghaffari
Mazandaran University of Medical Sciences
Outcome results
None listed