Polycystic ovary syndrome. Polycystic ovary syndrome
Conditions
Interventions
Intervention 1: Intervention group: usual diet plus less Liliaceous vegetables plus raw red onions (2 ×40-50 gr/ day for overweight and 2×50-60 gr/day for obese patients, one consumed with lunch and a
Treatment - Other
Intervention group: usual diet plus less Liliaceous vegetables plus raw red onions (2 ×40-50 gr/ day for overweight and 2×50-60 gr/day for obese patients, one consumed with lunch and another with dinn
control group: usual diet plus less Liliaceous vegetables plus raw red onions (2 ×10-15 gr/ day, one consumed with lunch and another with dinner) for 2 months
Sponsors
Vice-Chancellor for Research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
17 Years to 37 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Women diagnosed as PCOS by the Rotterdam consensus criteria (2003), age range: 17-37 years, 25<BMI<35, having insulin-resistance on screening, tendency to raw red onion consumption during the study, no tendency to pregnancy during the study, applying non-drug methods to prevent pregnancy during the study, low intake (<93g) of Liliaceaous vegetables Exclusion criteria: Any disease that affects metabolic parameters in this trial including Cushing's Syndrome, hypoglycemia, type I or II Diabetes, androgen secreting tumors or congenital adrenal hyperplasia, Hyperprolactinemia, hyperparathyroidism, thyroid disorders, gastrointestinal disorders (e.g. peptic ulcer), hypertension, anemia, Allergy, Asthma, cardiovascular, kidney, liver or pulmonary diseases, cancer, and any drug that affects glucose or insulin metabolism such as glucose-controlling drugs, contraceptives, glucocorticoids, anti-obesity drugs, multivitamins, beta-blockers (e.g. propranolol), anti-coagulants (e.g. Warfarin, Heparin? Clopidogrel), NSAIDS (e.g. Iboprofen and naproxen), Ginkgo biloba and omega3 at least 2 months before the onset of study, history of weight loss diet or a special diet during the
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hormonal parameters. Timepoint: the onset and end of the study. Method of measurement: serum levels of total testosterone, free testosterone, 17-OH progesterone, 17-ß stradiol, pregnenolone, 17-OH pregnenolone, LH, FSH, DHEAS, androstenedione, SHBG.;Metabolic parameters. Timepoint: the onset and the end of the study. Method of measurement: serum levels of fasting glucose and fasting insulin. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dietary pattern. Timepoint: the onset and end of the study. Method of measurement: 3-day food record and questinnaire of liliaceaous vegetables.;Obesity indices (waist circumference, BMI, Waist to hip ratio, and body composition). Timepoint: the onset and end of the study. Method of measurement: Waist circumference will be measured at a level midway between the lower rib margin and iliac crest with the tape all around the bare body in horizontal position without the pressure on the skin. BMI: weight (kg)/height (m) 2 WHR: waist circumference/hip circumference Body composition: Bioelectric impedance. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Saghafi Asl
Faculty of Health and Nutrition, Tabriz University Of Medical Sciences
Outcome results
None listed