Comparison between efficiency of two different doses of vitamin D injection in depressed patients with vitamin D deficiency on depressive symptoms

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201105306641N1

Enrollment

Registered

2011-10-16

Start date

2011-04-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Depressive episode

Interventions

Intervention 1: 1. 300000 IU Vitamin D injection. Intervention 2: 3. no treatment. Intervention 3: 2. 150000 IU Vitamin D injection.

Treatment - Drugs

1. 300000 IU Vitamin D injection

3. no treatment

2. 150000 IU Vitamin D injection

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with depression and serum 25(OH)D levels <40 nmol/L; no pregnancy and lactation, lack of vitamin and mineral supplementation and antidepressant drugs, without any thyroid ,CVD, kidney diseases. Exclusion criteria: Using vitamin and mineral supplementation and antidepressant drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Beck Depression score. Timepoint: Before and 3 months after intervention. Method of measurement: Beck Depression Inventory2 score.;Serum 25-hydoxy vitamin D [25-(OH) D]. Timepoint: Before and 3 months after intervention. Method of measurement: ELISA.	—

Secondary

Measure	Time frame
Serum Calcium. Timepoint: Before and 3 month after intervention. Method of measurement: laboratory.;Serum Phosphrous. Timepoint: Before and 3 month after intervention. Method of measurement: laboratory.;PTH. Timepoint: Before and 3 month after intervention. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mojtaba Yassini Ardekani

Yazd University of Medical Sciences and Health Services

yassiniard@yahoo.com , yassini@ssu.ac.ir+98 31516515

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026