Grade 1 or 2 bed sore. Decubitus ulcer (Pressure ulcer
Conditions
Interventions
Intervention 1: Control: topical placebo formulation (base of formulation without active ingredient of sildenafil) once daily for 14 days. Intervention 2: Intervention: topical sildenafil 10% once dai
Treatment - Drugs
Control: topical placebo formulation (base of formulation without active ingredient of sildenafil) once daily for 14 days
Intervention: topical sildenafil 10% once daily for 14 days
Sponsors
Pharmaceutical Research Center, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 139 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Grade 1 or 2 bed sore diagnosed by the pharmacist according to The 2-digit Stirling scale Exclusion criteria: pregnancy or lactation, hypersensitivity reaction to topical formulation, elevated ALT and/or AST to more than 3 times the upper limit of normal with clinical manifestations of liver failure or more than 5 times the upper limit of normal without clinical manifestations of liver failure, unwillingness for entering in the study or discontinuation of follow up
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of bed sore. Timepoint: 7 and 14 days after topical formulation. Method of measurement: evaluationof bed sore grade according to The 2-digit Stirling scale by pharmacist. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed