Diabetic Nephropathy. diabetic nephropathy
Conditions
Interventions
Intervention 1: Control group: In this study, patients in the placebo group will receive one capsule containing 125 mg carboxymethyl cellulose for 10 weeks. Diet evaluation will be performed using a 2
Sponsors
Nutrition Research Center, Tabriz University of medical Sciences, Tabriz, Iran
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: BMI =25 kg / m2 and BMI <38kg / m2 Age: 40 to 70 years Excretion of protein greater than 0.3 g in 24-hour urine for more than 3 months Willingness to participate in the study
Exclusion criteria
Exclusion criteria: Weekly consumption of okra over the past three months Pregnancy and lactation Other Kidney Diseases, Liver Disease, Thyroid disorders and Inflammatory Diseases, Cancer, NSAIDS consumption and so on. Energy intake less than 800 or more than 4,200 kcal per day based on a three-day feed record questionnaire Following unusual weight-loss regimens 3 months before the enrollment (like water treatment, single food eating, Canadian diet, ...) People taking warfarin or other anti-coagulants Cardiovascular Disease (Stages 2 and 3) Uncontrolled diabetes mellitus (HbA1c>8)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: enzymatic colorimetric.;HBA1c. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: chromatography.;Serum insulin. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: ELISA kit.;Homeostatic model assessment of insulin resistance. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: calculating with formula.;LDL-C. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: calculating with formula.;HDL-C. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Total cholesterol. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Triglyceride. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Serum Albumin. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Serum creatinine. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Blood urea nitrogen. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Urine Total Protein. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Urine creatinine. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Serum malondialdehyde. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Serum glitathione peroxidase. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Advanced glycation end products. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: laboratory kit.;Soluble receptor for advanced glycation end products. Timepoint: at baseline and 10 weeks after intervention. Method of measurement: l | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At baseline and three months after. Method of measurement: Digital Scales.;Waist. Timepoint: At baseline and three months after. Method of measurement: Non-elastic meter.;Blood pressure. Timepoint: At baseline and three months after. Method of measurement: Blood pressure Monitor.;Body fat percent. Timepoint: At baseline and three months after. Method of measurement: body composition devise.;Lean body mass percent. Timepoint: At baseline and three months after. Method of measurement: body composition devise.;Appetite. Timepoint: At baseline and three months after. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactomid nikpayam
Tabriz University of Medical Sciences
Outcome results
None listed