Submucous leiomyoma of uterus. Submucous leiomyoma of uterus
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, tranexamic acid ampoule with a dose of 0.5 g per 1000 cc of normal saline distending medium will be used (considering that the injection
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients with one submucosal myoma Myoma should be completely in the endometrial cavity or extending less than 50% into the myometrium (type 0 and 1, based on FIGO's classification) Myoma size less than 4 cm in the largest diameter confirmed by accurate transvaginal ultrasound Candidates for hysteroscopy and myomectomy
Exclusion criteria
Exclusion criteria: Pelvic infections History of uterine or cervical cancer; Hematological, cardiovascular, thromboembolic, hepatic, and renal disorders; or Thromboembolic events Taking anticoagulant agents Uterine septum, or uterine disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin Level. Timepoint: Once before surgery and once 24 hours after surgery. Method of measurement: Blood Test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of bleeding. Timepoint: Immediately after surgery. Method of measurement: Checklist.;Surgeon's field of view. Timepoint: Immediately after surgery. Method of measurement: Checklist.;Duration of surgery. Timepoint: Immediately after surgery. Method of measurement: Checklist.;The amount of medium used. Timepoint: Immediately after surgery. Method of measurement: Checklist.;Complications during surgery (Uterine perforation). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Completing myomectomy. Timepoint: Immediately after surgery. Method of measurement: Checklist.;Rare side effects of Tranexamic Acid (Pulmonary embolism). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Rare side effects of Tranexamic Acid (Headache). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Rare side effects of Tranexamic Acid (abdominal cramps). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Rare side effects of Tranexamic Acid (Weakness). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Rare side effects of Tranexamic Acid (Back Pain). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Rare side effects of Tranexamic Acid (Cramps and Muscle Spasms). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Complications during surgery (Thermal injury). Timepoint: Immediately after surgery. Method of measurement: Checklist.;Complications during surgery (Overload of distention media). Timepoint: Immediately after surgery. Method of measurement: Checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Venus Chegini
Tehran University of Medical Sciences
Outcome results
None listed