Comparison of the effect of OCP alone and in combination with N-acetylcysteine on clinical and ultrasound signs of endometrioma

Evaluation of the recurrence of dysmenorrhea,chronic pelvic pain and sonographic symptoms of endometrioma after laparoscopic surgery in the OCP alone treated group compared with the OCP plus N-acetylcysteine group

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110530006640N4

Enrollment

112

Registered

2018-04-16

Start date

2017-02-28

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian endometrioma. Endometriosis of ovary

Interventions

Intervention 1: Group 1: The first group will receive N-acetylcysteine 600 mg, three times a day, in 3 days a week for three months with continuous OCP for 6 months. Intervention 2: Group 2: The seco

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: being single Not having a tendency to pregnancy Diagnosis of ovarian endometrioma by ultrasound and confirmation by laparoscopic surgery

Exclusion criteria

Exclusion criteria: Patients who are planning a pregnancy after laparoscopic surgery

Design outcomes

Primary

Measure	Time frame
Ultrasound recurrence of endometrioma. Timepoint: Once before surgery and once 3 months after surgery and once at the end of the study (6 months after surgery). Method of measurement: Transvaginal ultrasonically assessment of the ovaries.;Dysmenorrhea recurrence. Timepoint: Once before surgery and once 3 months after surgery and once at the end of the study (6 months after surgery). Method of measurement: Visual Analog Scale (VAS).;Pelvic Pain Recurrence. Timepoint: Once before surgery and once 3 months after surgery and once at the end of the study (6 months after surgery). Method of measurement: Visual Analog Scale (VAS).	—

Measure

Time frame

Ultrasound recurrence of endometrioma. Timepoint: Once before surgery and once 3 months after surgery and once at the end of the study (6 months after surgery). Method of measurement: Transvaginal ultrasonically assessment of the ovaries.;Dysmenorrhea recurrence. Timepoint: Once before surgery and once 3 months after surgery and once at the end of the study (6 months after surgery). Method of measurement: Visual Analog Scale (VAS).;Pelvic Pain Recurrence. Timepoint: Once before surgery and once 3 months after surgery and once at the end of the study (6 months after surgery). Method of measurement: Visual Analog Scale (VAS).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Zahra Asgari

Tehran University of Medical Sciences

asgariza@sina.tums.ac.ir+98 21 7788 8755

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026