Comparison of depth of anesthesia with Midazolam+ Na Thiopental and Midazolam +Propofol in cesarean section

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201105296625N1

Enrollment

Registered

2011-06-27

Start date

2011-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia in Cesarean section. Complications of anaesthesia during labour and delivery

Interventions

Intervention 1: Metoclopramide10mg , Midazolam 1.5 mg , lidocaine 1.5mg/kg+ Propofol 2.5 mg/kg+ Succynil choline 1.5 mg/kg IV, single Dose. Intervention 2: Metoclopramide10mg , Midazolam 1.5 mg

Metoclopramide10mg , Midazolam 1.5 mg , lidocaine 1.5mg/kg+ Propofol 2.5 mg/kg+ Succynil choline 1.5 mg/kg IV, single Dose

Metoclopramide10mg , Midazolam 1.5 mg , lidocaine 1.5mg/kg+ Na thiopental 5 mg/kg+ Succynil choline 1.5 mg/kg IV, single Dose

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: patients undergoing elective C/S; age range 18-40; ASA Class I,II; Mallampati class I,II Exclusion Criteria : History of respiratory and cardiovascular diseases; HTN; Addiction; Multiple Gestation; Emergency C/S; Predicted difficult airway

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Depth of anesthesia. Timepoint: before intervention until end of surgery and extubation. Method of measurement: By Bispecteral Index System.	—

Secondary

Measure	Time frame
BIS Values. Timepoint: At time of lying on surgical table, Induction , Intubation, Skin incision, 5 min after delivery and administering narcotics, discontinuing volatile anesthetics and extubation. Method of measurement: By Bispecteral Index System.;Hemodynamic parameters. Timepoint: At time of lying on surgical table, Induction , Intubation, Skin incision, 5 min after delivery and administering narcotics, discontinuing volatile anesthetics and extubation. Method of measurement: ECG, Pulse oximeter, Sphygmomanometer.;Newborn APGAR Score. Timepoint: 1 and 5 min after delivery. Method of measurement: Visual -Examination.;PH and Blood Gases in newborn umbilical Artery. Timepoint: After delivery. Method of measurement: Arterial Blood Gas.	—

Measure

Time frame

BIS Values. Timepoint: At time of lying on surgical table, Induction , Intubation, Skin incision, 5 min after delivery and administering narcotics, discontinuing volatile anesthetics and extubation. Method of measurement: By Bispecteral Index System.;Hemodynamic parameters. Timepoint: At time of lying on surgical table, Induction , Intubation, Skin incision, 5 min after delivery and administering narcotics, discontinuing volatile anesthetics and extubation. Method of measurement: ECG, Pulse oximeter, Sphygmomanometer.;Newborn APGAR Score. Timepoint: 1 and 5 min after delivery. Method of measurement: Visual -Examination.;PH and Blood Gases in newborn umbilical Artery. Timepoint: After delivery. Method of measurement: Arterial Blood Gas.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Seyed Mozaffar Rabiee

Babol University Of Medical Sciences

drm_rabiee@yahoo.com+98 11 1223 8296

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026