Condition 1: Submucous leiomyoma. Condition 2: endometrial tickness. Condition 3: Polyp of corpus uteri. Submucous leiomyoma of uterus Endometrial glandular hyperplasia Polyp of corpus uteri
Conditions
Interventions
Intervention 1: Group A: E-Aminocaproeic Acid in dextrose 5% inside one liter of the dextrose 5%. Intervention 2: Group B: placebo i.e., dextrose 5% in the same form inside one liter of the dextrose
Placebo
Treatment - Drugs
Group B: placebo i.e., dextrose 5% in the same form inside one liter of the dextrose 5%
Sponsors
Women's Reproductive Health Research Center, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: history of persistent uterine bleeding accompanied with endometrial thickness, endometrial polyp or submucous myoma less than 3 cm in diameters and patients' willing to participate Exclusion criteria: Patients with the history of cardiopulmonary and liver disease, hypertension, diabetes, hyperlipidemia, cervical and uterine cancers, submucous myomas more than 3 cm in diameters
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interaoperative bleeding. Timepoint: at the end of surgery. Method of measurement: Visual scale.;Duration of surgery. Timepoint: from the beginning to the end of surgery. Method of measurement: time based on minute.;Volume of injected media. Timepoint: after finishing of every one litre serum. Method of measurement: number of injected serums.;Success in completion of operation. Timepoint: from the beginning to the end of surgery. Method of measurement: based on miutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Post operative bleeding. Timepoint: every 15 minuts. Method of measurement: clinical signs and symptoms.;Blood pressure. Timepoint: continious. Method of measurement: monitor.;Bradycardia. Timepoint: continious. Method of measurement: monitor.;Gastrointestinal side effects. Timepoint: every 1 hour. Method of measurement: clinical signs and symptoms.;Headache. Timepoint: every 1 hours. Method of measurement: clinical symptoms.;Leg muscles cramp. Timepoint: every 6 hours. Method of measurement: clinical symptoms.;Duration of hospital stay. Timepoint: every 6 hours. Method of measurement: hours. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactManizheh Sayyah-Melli
Tabriz University of Medical Sciences
Outcome results
None listed