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comparative study of natural micronized progestrone and gonadotropin-releasing hormone agonist in the control of bleeding during hysterescopic myomectomy in women with abnormal uterine bleeding

comparative study of natural micronized progestrone and gonadotropin-releasing hormone agonist in the control of bleeding during hysterescopic myomectomy in women with abnormal uterine bleeding

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110523006563N3
Enrollment
50
Registered
2018-01-04
Start date
2018-01-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal uterine and vaginal bleeding. Other abnormal uterine and vaginal bleeding

Interventions

Intervention 1: Intervention group 1 : A 100 mg capsule of natural micronized progesterone called Utrogestan will be used, starting from the first day of the period for 30 days, two capsules of 200 mg
Treatment - Drugs
Intervention group 1 : A 100 mg capsule of natural micronized progesterone called Utrogestan will be used, starting from the first day of the period for 30 days, two capsules of 200 mg will be used at
Intervention group 2: Intramuscular injection of 3.75 mg of diafililic ampoule as a GnRH agonist compound will be used on day 21 of the period two dose intervals of 28 days for 2 months prior to the h

Sponsors

Vice chancellor for Research,Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients with abnormal uterine bleeding Patients with submucosal myoma with a diameter of 30 mm or less and zero or first grade

Exclusion criteria

Exclusion criteria: : Patients with a history of heart disease; Hepatic; Diabetes; Thromboembolism; Cancer of the uterus and cervix; Submucosal leiomyoma larger than 3 cm; Uterine septum; pregnant women; Severe bleeding; Anti coagulation therapy

Design outcomes

Primary

MeasureTime frame
The hemoglobin concentration. Timepoint: Six hours after surgery. Method of measurement: Blood test.

Secondary

MeasureTime frame
Duration of surgery. Timepoint: After surgery. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehri Jaefari Shobeiri

Tabriz University of Medical Sciences

lahhroudin@gmail.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026