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Antibiotic prophylaxis roles in success of myringoplasty

Antibiotic prophylaxis roles in success of myringoplasty in patients with eardrum perforation

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201105222821N5
Enrollment
200
Registered
2011-06-11
Start date
2010-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic otitis media. Nonsuppurative otitis media

Interventions

Intervention 1: Group A: 1gr. sefazolin 1 hour before beginning of surgery and every 6 hours after surgery until 24 hours. Intervention 2: Group B: 1gr. sefazolin 1 hour before beginning of surgery an
Treatment - Drugs
Group A: 1gr. sefazolin 1 hour before beginning of surgery and every 6 hours after surgery until 24 hours
Group B: 1gr. sefazolin 1 hour before beginning of surgery and every 6 hours after surgery until 24 hours and then 500mg cephalexin capsule every 6 hours until 10 days

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1.patients with eardrum perforation, 2. no discharge of ear for 2 months, 3.no other pathology in middle ear. Exclusion criteria: 1. patients with active ear discharge, 2. other pathology of middle ear, 3.systemic diseases such as diabetes, 4.no satisfaction of patient

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Eardrum healing. Timepoint: 8 weeks. Method of measurement: examination and audiometry.

Secondary

MeasureTime frame
Infection of ear. Timepoint: 1, 2, 4, 8 weeks. Method of measurement: examination and otoscopy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefe Nourmohamadi

Tabriz University of Medical Sciences

a.nourmohamadi@yahoo.com+98 41103347054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026