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A comparison of Propofol with ketofol (a Ketamine-Propofol combination) for sedation during hysteroscopy in patient in IVF operation room

A comparison of Propofol with ketofol (a Ketamine-Propofol combination) for sedation during hysteroscopy in patient in IVF operation room

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201105176510N1
Enrollment
40
Registered
2012-02-14
Start date
2011-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parenteral anaesthetics. Parenteral anaesthetics

Interventions

Intervention 1: Intervention group: combination of ketamine and propofol to 5mg/kg of each drugs that inject to patients to 1 mg/kg of propofol. Intervention 2: Control group: combination of propofol
Treatment - Drugs
Placebo
Intervention group: combination of ketamine and propofol to 5mg/kg of each drugs that inject to patients to 1 mg/kg of propofol.
Control group: combination of propofol with sterile water to 5mg/kg of propofol that inject to patients to 1 mg/kg of propofol.

Sponsors

Ahwaz Jondi Shapur University of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age under 40y, ASA class 1&2, no cardiovascular risk factor, no history of reaction to egg or soy bean & Ketamine or propofol, no psychiatric history, no history of airway difficulty. Exclusion criteria: airway difficulty like difficult ventilation, change of hysteroscopy to open surgery or complicated hysteroscopy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Depth of anesthesia. Timepoint: 5 minute after induction of anesthesia. Method of measurement: with Bispecteral Index Score device.

Secondary

MeasureTime frame
Incidence of apnea. Timepoint: in time of anesthesia. Method of measurement: observation of anesthesiologist.;Incidence of nausea & vomiting. Timepoint: in time of anesthesia & recovery. Method of measurement: observation of anesthesiologist.;Systolic blood pressure. Timepoint: before & 5 minute after induction of anesthesia. Method of measurement: automatic blood pressure device.;Pulse rate. Timepoint: before & 5 minute after induction of anesthesia. Method of measurement: ECG monitoring device.;Psychiatric side effect. Timepoint: recovery period. Method of measurement: observation of anesthesiologist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Amin Mousavian Roshan Zamir

Ahwaz Jondi Shapour University of medical sciences

amin_vw@yahoo.com+98 61 1222 2114

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026