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The effect of doxycycline and zinc sulfate in acne

The study of the clinical effectiveness of doxycycline capsule with zinc sulfate on the treatment of patients with acne vulgaris

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201105156493N1
Enrollment
80
Registered
2011-06-30
Start date
2010-10-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acne vulgaris. Disease of skin appendages

Interventions

Intervention 1: Control group: Doxycycline, 100mg, daily, for 12 weeks. Intervention 2: Intervention group: Zinc sulphate, 30mg, daily for 12 weeks.
Treatment - Drugs
Control group: Doxycycline, 100mg, daily, for 12 weeks
Intervention group: Zinc sulphate, 30mg, daily for 12 weeks

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 18-40 years old – mild to moderate acne – acne since more than 2 months ago Exclusion criteria: severe and nodulocystic acne – pregnancy and breast feeding – other skin disease in face – use of systemic and topical steroids, lithium, B group vitamins, iodide or bromium, antibacterial soap and antiseptic soloutions, oral and topical antibiotics and zinc and systemic and topical anti acne drugs in recent 1 month and isotretinoin in recent 2 months and antiacid drugs and calcium and iron based agents

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Acne improvment. Timepoint: Before intervention, 4 Weeks later, 8 weeks later, 12 weeks later. Method of measurement: Counting of lesions (scoring).

Secondary

MeasureTime frame
Decrease of inflammatory and non inflammatory lesions. Timepoint: Before intervention, 4 weeks later, 8 weeks later, 12 weeks later. Method of measurement: Counting of lesions(scoring).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Effat Khodaeiani

Tabriz University of Medical Sciences

dr.khodaeiani@tbzmed.ac.irdrekhodaeiani@yahoo.comad@1271@yahoo.com+98 41 1541 2101

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026