acute myocardial infarction. Acute myocardial infarction
Conditions
Interventions
Intervention 1: Intervention group are prescribed 25 mcg/kg of bolus intravenous tirofiban in 1-3 minutes as soon as possible in the emergency department. Intervention 2: The control group will not r
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Acute myocardial infarction patient with ST segment elevation or new left bundle branch block in 12 hours of onset of symptoms and are candidate for primary PCI within 90 minutes of presentations to the emergency department
Exclusion criteria
Exclusion criteria: Exclusion criteria: Stroke or TIA within the past 30 days or any history of hemorrhagic stroke, well known intra cranial disease (neoplasm or aneurysm), any active bleeding or bleeding history in past 30 days, uncontrolled HTN at registry time (SBP>180, DBP>110), Major operation or trauma in recent 6 weeks, platlete count less than 100000 or bleeding conditions, Coagulation disorders (INR>1.5), Severe hepatic failure, Administration of any fibrinolytic treatment 24 hours from randomization, Renal failure (Cr>205mg/dl or GFR <30), age more than 75 years old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of TIMI 3 flow score in coronary angiography. Timepoint: in cath lab before PCI. Method of measurement: according to angiography report. | — |
Secondary
| Measure | Time frame |
|---|---|
| Major Cardiac Event. Timepoint: one year. Method of measurement: clinical follow up. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Seyed Hesameddin Abbasi
Tehran Heart Center
Outcome results
None listed